Results 81 to 90 of about 2,426,264 (355)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Socioeconomic inequality in Hepatitis B vaccination of rural adults in China

Human Vaccines & Immunotherapeutics, 2018
Hepatitis B (HB) vaccination is the most effective way to prevent HB virus infection. While measures taken to control the prevalence of HB have achieved significant results, HB prevalence in rural China among adults remains problematic.
Dawei Zhu, Na Guo, Jian Wang, Stephen Nicholas, Zhen Wang, Guojie Zhang, Luwen Shi, Knut Reidar Wangen   +7 more
doaj   +1 more source

Calculating the concentration index when income is grouped

Journal of Health Economics, 2010
The problem introduced by grouping income data when measuring socioeconomic inequalities in health (and health care) has been highlighted in a recent study in this journal. We re-examine this issue and show there is a tendency to underestimate the concentration index at an increasing rate when lowering the number of income categories.
Clarke, P, Van Ourti, Tom
openaire   +3 more sources

Natriuretic peptides and integrated risk assessment for cardiovascular disease. an individual-participant-data meta-analysis [PDF]

, 2016
BACKGROUND: Guidelines for primary prevention of cardiovascular diseases focus on prediction of coronary heart disease and stroke. We assessed whether or not measurement of N-terminal-pro-B-type natriuretic peptide (NT-proBNP) concentration could enable ...
Adam S, Butterworth, Andreas, Luchner, Angela M, Wood, Brendan, M. Everett, Børge G, Nordestgaard, Caroline, N. Kistorp, Christie M, Ballantyne, Christopher, Defilippi, Daniel F, Freitag, Daniel, Levy, Demosthenes, B. Panagiotakos, DI ANGELANTONIO, EMANUELE, Frank, Kee, Goya Wannamethee, S, James A, de Lemos, Jari A. Laukkanen, Maryam Kavousi, Jens, Rosenberg, Johan, Ärnlöv, John, Danesh, Jonas, Andersson, Jorge R, Kizer, Juan Pablo, Casas, Jukka, T. Salonen, Jussi, Kauhanen, Lars, Lind, Lisa, Pennells, Lori B, Daniels, Mary, Cushman, Michael, Hecht Olsen, Michael, Sweeting, Nancy, R. Cook, Naveed, Sattar, Olle, Melander, Oscar, H. Franco, Paul M, Ridker, Pei, Gao, Peter, Willeit, Rajiv, Chowdhury, RUBATTU, Speranza Donatella, Rudolf, A. de Boer, Sarah, A. Spackman, Simon G, Thompson, Stefan, Kiechl, Stella, Trompet, Stephen Kaptoge, Paul Welsh, Stephen, Burgess, Suzanne, Judd, Thomas, Mueller, Torben, Jørgensen, Toshiharu, Ninomiya, Veikko, Salomaa, Vijay, Nambi, Vilmundur, Gudnason, Wayne, D. Rosamond   +53 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Investigation of Status of Socioeconomic Inequalities in Satisfaction with Life in Women Aged 15-54 in Iran

مجله اپیدمیولوژی ایران, 2018
Background and Objectives: Life satisfaction is one of the important dimensions of health, which is influenced by health determinants. The aim of this study was to investigate the status of socioeconomic inequalities in satisfaction with life in women ...
E Goodarzi, GH Moradi, A Khosravi, N Esmailnasab, B Nouri, A Delpisheh, E GHaderi, D Roshani   +7 more
doaj  

Inequalities changes in health services utilization among middle-aged and older adult disabled people in China: based on CHARLS 2011–2018

Frontiers in Public Health
BackgroundMultiple intersections, including socioeconomic inequalities, influence health equity for disabled people and sub-populations. However, this association has not been sufficiently analyzed among Chinese-impaired persons.
Shengxuan Jin, Shengxuan Jin, Ruobing Fa, Jiaqi Wu, Jiawei Lin, Shuyuan Zhang, Majid Ali, Shaofan Chen, Dongfu Qian, Dongfu Qian   +9 more
doaj   +1 more source

On correcting the concentration index for binary variables

Journal of Health Economics, 2013
This article discusses measurement of socioeconomic inequalities in the prevalence of a health condition, in response to the recent exchange between Guido Erreygers and Adam Wagstaff, in which they discuss the merits of their own corrections to the frequently used concentration index.
Kjellsson, Gustav, Gerdtham, Ulf-G.
openaire   +2 more sources

Erodibility of hill peat [PDF]

, 2006
peer-reviewedThe project was funded by the European Union Structural Funds EAGGF distributed under the Department of Agriculture and Food Stimulus Fund.The energy necessary to entrain soil in water depends on the soil strength.
Healy, Mark G., Marren, N., Mulqueen, J., Rodgers, M.   +3 more
core   +1 more source