Results 131 to 140 of about 1,419,473 (306)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Relationship between Design Concept and Sketches of Architectural Design Novices
, 2013 [[abstract]]Most architects use concrete forms to help them develop ideas. Such process is commonly found in conceptual sketching and abstract graphics.
Shih-Yung Liu; Yi-Ching Liu; Hsiu-Tyan Chuang
core
An Integrated Decision Making Model for Evaluation of Concept Design
Acta Polytechnica, 2004 The Conceptual design phase generates various design concepts and these are then evaluated in order to identify the 'Best’ concept. Identifying the Best concept is important because much of the product life cycle cost is decided in this phase.
G. Green, G. Mamtani
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
We are Designers Because We Can Abstract [PDF]
, 2009 Organised by: Cranfield UniversityDue to the increasing systems complexity, architecture design became an important issue. It gained interest and its importance was framed in three domains: as a way to understand complex systems, to design them, to ...
Adel, A., Djeridi, R.
core
Exploring designers’ cognitive abilities in the concept product design phase through traditional and digitally-mediated design environments [PDF]
DESIGN2024 18th International Design Conference, May, 20-23, 2024, Cavtat, Dubrovnik, Croatia202405 bcchVersion of RecordRGCPublishedCUP (2024 ...
Tufail, M +4 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
27.13 S91-41174 Flight design, concept
This image reflects a drawing of the Waste Collection System.
core
Materializing “Ruling Relations” : A Case of Gender, Power and Elder Care in Sweden [PDF]
, 2017 This paper reflects upon our critical (feminist) design research approach developed in response to the Swedish Governmental Agency for Innovation Systems (Vinnova)’s innovation program on equality.
Isaksson, Anna +4 more
core
Applying 3D scanning and modeling in transport design education
, 2006 Advanced 3D Laser Scanning processes have developed over the last decade and are now available and affordable for medium to large companies as well as education.
Unver, Ertu +3 more
core +1 more source