Results 111 to 120 of about 1,419,473 (306)

The General Registry of Autologous Fat Transfer: Concept, Design, and Analysis of Fat Grafting Complications. [PDF]

Plast Reconstr Surg, 2022
Kaur S, Rubin JP, Gusenoff J, Sommers CA, Shamsunder MG, Hume KM, Mehrara BJ.   +6 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Integrated design and PLM applications in aeronautics product development [PDF]

, 2009
Organised by: Cranfield UniversityWell known challenges in Aeronautic industry, namely reducing time to market, risks and development costs, could be reached thanks to innovative design methods supported by PLM technologies.
EYNARD, Benoit, TROUSSIER, Nadège, ROUCOULES, Lionel, Eynard, B., Ducellier, G., DUCELLIER, Guillaume, Belkadi, F., van Wijk, D., Roucoules, L., Troussier, N., VAN WIJK, Dimitri, BELKADI, Farouk   +11 more
core  

Construction and Application of Data Model in the Maritime Stereotactic Space Use

Haiyang Kaifa yu guanli
Marine stereotactic space management is an effective way to optimize ocean space and improve the utilization efficiency of marine resources. Purpose of the study is to set up digital and automatic management of the stereo right to use marine.
LI Shanchi, PENG Yihuan
doaj  

Concept, Design, and Early Prototyping of a Low-Cost, Minimally Invasive, Fully Implantable Left Ventricular Assist Device. [PDF]

Bioengineering (Basel), 2022
Pleșoianu FA, Pleșoianu CE, Bararu Bojan I, Bojan A, Țăruș A, Tinică G.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Happy moments: A well-being driven design of a Car2Go

, 2016
User well‐being is increasingly addressed in design and design research. Previous work has proposed a design for well-¬‐being framework that includes three main ingredients: pleasure, personal significance, and virtue. While useful for analysing the well-
Duste, Tessa, van Grondelle, Elmer, Duste, T. (author), Tessa Duste, Elmer van Grondelle, Pieter Desmet, Desmet, Pieter, Desmet, P.M.A. (author), van Grondelle, E.D. (author)   +8 more
core   +1 more source

Concept design of the physical structure for ICU ventilators for COVID-19 pandemic. [PDF]

Sens Int, 2021
Agarwal KM, Sharma P, Bhatia D, Mishra A.   +3 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

From sign to design: The role of domain transfer in redefining architecture locality

ARTEKS : Jurnal Teknik Arsitektur
This research examines the design process using conceptual frameworks based on domain transfer to suggest a new model for architecture based on local contexts.
Bramasta Putra Redyantanu, Rony Gunawan Sunaryo   +1 more
doaj   +1 more source