Results 51 to 60 of about 22,041,249 (385)
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers +5 more
wiley +1 more source
Learning relationships from theory to design [PDF]
This paper attempts to bridge the psychological and anthropological views of situated learning by focusing on the concept of a learning relationship, and by exploiting this concept in our framework for the design of learning technology.
Fowler, C.J.H., Mayes, J.T.
core +4 more sources
ABSTRACT Background Transfusion‐related iron overload (TRIO) is a late effect of therapy impacting survivors of childhood cancer and hematopoietic stem cell transplantation (HSCT) who receive frequent packed red blood cell (pRBC) transfusions. Surprisingly, there are no accepted guidelines to assist providers in identifying and treating at‐risk ...
Luke Gingell +3 more
wiley +1 more source
Design concept development in transportation design [PDF]
The paper presents results of a study about design concept development in transportation design. The main question of this study concerns mainly the existence and development of design concepts and its status in the design process furthermore it ...
Krzywinski, Jens
core
A robust design methodology suitable for application to one-off products [PDF]
Robust design is an activity of fundamental importance when designing large, complex, one-off engineering products. Work is described which is concerned with the application of the theory of design of experiments and stochastic optimization methods to ...
COATES G. +5 more
core +2 more sources
Concept design of the LiteBIRD satellite for CMB B-mode polarization
LiteBIRD is a candidate for JAXA’s strategic large mission to observe the cosmic microwave background (CMB) polarization over the full sky at large angular scales.
Y. Sekimoto +156 more
semanticscholar +1 more source
Sequence-based drug design as a concept in computational drug design
Drug development based on target proteins has been a successful approach in recent decades. However, the conventional structure-based drug design (SBDD) pipeline is a complex, human-engineered process with multiple independently optimized steps. Here, we
Lifan Chen +23 more
semanticscholar +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Primary Response Assessment Method for Concept Design of Monotonous Thin-Walled Structures
A concept design methodology for monotonous, tapered thin-walled structures (wing/fuselage/ship/bridge) is presented including modules for: model generation; loads; primary (longitudinal) and secondary (transverse) strength calculations; structural ...
V. Zanic, P. Prebeg
doaj
Konsep pembagian pecahan masih merupakan konsep yang sulit bagi sebagian besar siswa. Banyak siswa SD maupun SMP belum dapat menulis dengan benar rumus pembagian pecahan .
Firman Pangaribuan +2 more
doaj +1 more source

