Results 111 to 120 of about 95,304 (285)

Exploring the Lived Experiences of Individuals with Amyotrophic Lateral Sclerosis (ALS): A Qualitative Study and Conceptual Model of Signs, Symptoms, and Functional Impacts

open access: yesNeurology and Therapy
Introduction This study aimed to explore the experience of living with amyotrophic lateral sclerosis (ALS) and to develop a conceptual model for this rare disease. Methods Concept elicitation interviews were conducted (January–September 2024) with people
William B. Nowell   +7 more
doaj   +1 more source

Content validity of the Migraine-Specific Quality of Life Questionnaire version 2.1 electronic patient-reported outcome

open access: yesJournal of Patient-Reported Outcomes, 2019
Purpose A concept elicitation, cognitive debriefing, and usability study was undertaken to: 1) ascertain the migraine experience with a particular focus on the impact on roles and daily functioning; 2) determine the comprehensiveness and ...
Rebecca M. Speck   +5 more
doaj   +1 more source

Co-constructing early adolescent education through image-based research : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education at Massey University, Palmerston North [PDF]

open access: yes, 2006
Professional literature reporting the needs and characteristics, both educational and developmental of early adolescents presents a compelling case that students of this age group are distinct and require the development of a unique educational approach ...
Nelson, Emily Jane
core  

Smart Conversational Agents for Reminiscence

open access: yes, 2018
In this paper we describe the requirements and early system design for a smart conversational agent that can assist older adults in the reminiscence process.
Caforio Valentina   +6 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

A systematic review of the use and quality of qualitative methods in concept elicitation for measures with children and young people:Review of qualitative concept elicitation with children and young people [PDF]

open access: yes, 2020
Background: Qualitative research is recommended in concept elicitation for patient reported outcome measures to ensure item content validity, and those developing measures are encouraged to report qualitative methods in detail. However, in measure development for children and young people, direct research can be challenging due to problems with ...
Husbands, Samantha   +2 more
openaire   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Students' affordance of teleologic explanations and antrhropomorphic language in eliciting concepts in physics

open access: yesJournal of Technology and Science Education, 2015
This study ascertains the students’ affordance of teleologic explanations and anthropomorphic language in eliciting concepts in Physics as influenced by their age and learning exposure and experience. Using Explicative-Reductive Method of Descriptive Research, this study focused on the determinants of students’ affordance of teleologic-anthropomorphic ...
openaire   +6 more sources

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

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