Results 71 to 80 of about 2,784,856 (344)

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

Quality of life: considerations about concept and instruments of measure.

open access: yesOnline Brazilian Journal of Nursing, 2007
The concept of quality of life has been having more and more attention in scientific literature in different areas, specially nursing. It is a concept with many meanings, different possibilities of focusing and uncountable and controversial theories and ...
Milena Butolo Vido   +1 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

“And a door opens”: reflections on conceptual and identity issues on clinical reasoning in occupational therapy

open access: yesCadernos Brasileiros de Terapia Ocupacional, 2019
Introduction: Placing practice in words is an arduous task for occupational therapists by considering the narrative aspects of practice in the complex and multifaceted relationships between human beings and society.
Taís Quevedo Marcolino   +4 more
doaj  

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

SERKET: An Architecture for Connecting Stochastic Models to Realize a Large-Scale Cognitive Model

open access: yesFrontiers in Neurorobotics, 2018
To realize human-like robot intelligence, a large-scale cognitive architecture is required for robots to understand their environment through a variety of sensors with which they are equipped. In this paper, we propose a novel framework named Serket that
Tomoaki Nakamura   +2 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The structure and formation of natural categories [PDF]

open access: yes
Categorization and concept formation are critical activities of intelligence. These processes and the conceptual structures that support them raise important issues at the interface of cognitive psychology and artificial intelligence.
Fisher, Douglas, Langley, Pat
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Chronic health conditions in adults: concept analysis Condición crónica de salud del adulto: análisis de concepto Condição crônica: análise do conceito no contexto da saúde do adulto

open access: yesRevista Latino-Americana de Enfermagem, 2007
This study aimed to define the concept of chronic health condition in adults as presented in literature. An evolutionary perspective of concept analysis was used, as presented by Rodgers, emphasizing the essential attributes, antecedents, consequences ...
Maria Célia de Freitas   +1 more
doaj   +1 more source

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