Results 71 to 80 of about 11,191,832 (394)
FEBS Letters, EarlyView.Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa +8 more
wiley +1 more source
HR: A System for Machine Discovery in Finite Algebras [PDF]
, 1998 We describe the HR concept formation program which invents mathematical definitions and conjectures in finite algebras such as group theory and ring theory.
Bundy, Alan, Colton, S., Walsh, T.
core +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Whatever happened to meaning? Commentary on Millikan: A common structure for concepts of individuals, stuffs, and real kinds [PDF]
, 1998 Even in infancy, concept formation has to do with creating meaning, not with tracking substances. Preverbal infants can identify a substance such as a dog, but their first concept of this substance is not dog but animal.
Mandler, JM
core
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Notes on the “Self-Centered” Factor, Based on Data from Child Language Acquisition [PDF]
Psychology in Russia: State of Art, 2019 Background. Tis study is based on large samples of language-data collected during the formative period of language acquisition (9–62 months) from free dialogues of English and French children.
Velina Slavova
doaj +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
, 2013 Natural structure with respect to a given doctrine is thus a precise mathematical model for a very general scientific process of concept formation.
openaire +2 more sources
Concepts in CMB anisotropy formation [PDF]
, 2007 These lecture notes form a primer on the theory of cosmic microwave background (CMB) anisotropy formation. With emphasis on conceptual aspects rather than technical issues, we examine the physical foundations of anisotropy evolution in relativistic kinetic and perturbation theory as well as the manifestation of these principles in primary and secondary
openaire +4 more sources
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source