Results 81 to 90 of about 2,784,856 (344)

Structure learning enhances concept formation in synthetic Active Inference agents. [PDF]

PLoS One, 2022
Neacsu V, Mirza MB, Adams RA, Friston KJ.   +3 more
europepmc   +1 more source

A Simulation Study on Multicomponent Lipid Bilayer

, 2005
Simulation of a multicomponent lipid bilayer having a fixed percentage of cholesterol is done to study phase transition leading to domain formation.
Anderson, Anderson, Banerjee, Banerjee, Ben-Shaul, Bloom, Brown, Brown, Brown, de Miguel, Doniach, Ermoshkin, Evans, Ferrenberg, Harrison, Jacobson, Jayashree Saha, Lee, May, Mouritsen, Nielsen, Nielsen, Radhakrishnan, Sabra, Scherfeld, Simons, Simons, Srilekha Banerjee, Zhang   +28 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Influence of language on perception and concept formation in a brain-constrained deep neural network model. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Henningsen-Schomers MR, Garagnani M, Pulvermüller F.   +2 more
europepmc   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Nursing diagnosis proposal "Impaired Peripheral Venous Return": concept formation. [PDF]

Rev Bras Enferm, 2023
Medeiros HPDS, Araújo JNM, Silva ABD, Dantas RAN, Lopes CT, Vitor AF.   +5 more
europepmc   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Kick-starting concept formation with intrinsically motivated learning: the grounding by competence acquisition hypothesis. [PDF]

Philos Trans R Soc Lond B Biol Sci, 2023
Mannella F, Tummolini L.
europepmc   +1 more source

Formation of Ecosystem Marketing Concept

Journal of Environmental Management and Tourism, 2018
Economic ecosystems were considered in the paper. The concept of ecosystem marketing was proposed and disclosed. The effective functioning of ecosystems facilitates mutual with the consumer and other interested parties creation of values, allows working quicker with less expenditures, with risk sharing, making reasonable decisions in the real time mode.
Sekerin V.D., Gorlevskaya L.E., Gusov A.Z., Gorokhova A.E.   +3 more
openaire   +3 more sources

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source