Results 71 to 80 of about 3,453,259 (246)
“If I Get Home Safe”: William C. White’s Experiences in the American Civil War [PDF]
, 2015 core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Letting the Finite Vanish: Hegel, Tillich, and Caputo on the Ontological Philosophy of Religion* [PDF]
, 2015 In general, Kant’s critique of metaphysics still holds up, especially for religious metaphysics. This situation does not necessarily debunk the truth of either position, but it has produced, as Lyotard wrote, a “postmodern condition” defined by ...
core +1 more source
Jurnal BIOEDUIN, 2018 The purpose of this study was to determine the effect of KWL strategy on students' mastery of the material concept of ecosystems. The hypothesis of this study is the use of learning strategies KWL on ecosystem material and significant positive effect on ...
Nia Kurniasih, Milla Listiawati
doaj +1 more source
Application of a Markov Chain Traffic Model to the Greater Philadelphia Region [PDF]
, 2015 A macroscopic traffic model based on the Markov chain process is developed for urban traffic networks. The method utilizes existing census data rather than measurements of traffic to create parameters for the model.
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The Untold Stories of Mormonism Exposed: Material Culture, Dime Novels, and Mormonism in American Society [PDF]
, 2015 This paper is an object biography of the dime novel Mormonism Exposed, considering the book in relation to dime novels and American Mormonism. Published in 1896 by the genre fiction publisher J.
core +1 more source