Results 81 to 90 of about 22,151 (256)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Penguasaan Konsep dan Keterampilan Proses Sains Siswa Kelas XII pada Materi Fluida Statis

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2018
This study aims to describe the mastery of the concept and students' science process skills of static fluid materials. Descriptive research method. The study was conducted on 162 students of SMAN 1 Masbagik.
Ahmad Yadaeni   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

THE USE OF DIFFICULTY LEARNING ASSESSMENT IN ASSESSING THE CONCEPT MASTERY OF BIOLOGY TEACHER CANDIDATES ON DEVELOPMENT STAGE OF ANIMAL EMBRIOLOGY

open access: yesJurnal Penelitian dan Pembelajaran IPA, 2017
This study aims to obtain a description of the mastery of the concept of biology teacher candidates through the study of learning difficulties in the concept of development stage of animal embryo.
Aa Juhanda
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Bagaimana Penguasaan Konsep Siswa pada Materi Fluida Statis?

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2019
: The purpose of this study is to determine the increase of mastery concept in static fluid in inquiry learning with theoretical empirical reviews. The research method uses descriptive analysis.
Atika Isnaining Dyah   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Penguasaan Konsep Siswa pada Model Pembelajaran Interactive Demonstration disertai Formative Feedback

open access: yesJurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2018
: This research was aimed to analyze the mastery of the concept of pressure on interactive demonstration learning model with formative feedback. The study involved 45 students of class VIII SMP Negeri 2 Rembang. The learning process is designed using the
Suryaningsasi Suryaningsasi   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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