Results 101 to 110 of about 348,254 (301)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

PENGUASAAN KONSEP SISWA PADA MATERI EKOSISTEM MELALUI PENERAPAN MODEL PROBLEM POSING LEARNING BERBASIS DONGENG SAINS (PPL-DS)

open access: yesJurnal BIOEDUIN, 2019
This research generally is aimed to recognize the students’ concept mastery on ecosystem material by using the Problem Posing Learning (PPL) based on science fables and its influence on the students and student responses and delays in learning were ...
Jaelani Fitri   +2 more
doaj   +1 more source

Assessing concept possession as an explicit and social practice [PDF]

open access: yes, 2017
We focus on issues of learning assessment from the point of view of an investigation of philosophical elements in teaching. We contend that assessment of concept possession at school based on ordinary multiple-choice tests might be ineffective because it
Marabini, Alessia, Moretti, Luca
core   +1 more source

A probabilistic generative model for tracking multi-knowledge concept mastery probability

open access: yesFrontiers of Computer Science
Knowledge tracing aims to track students' knowledge status over time to predict students' future performance accurately. Markov chain-based knowledge tracking (MCKT) models can track knowledge concept mastery probability over time. However, as the number of tracked knowledge concepts increases, the time complexity of MCKT predicting student performance
Liu, Hengyu; id_orcid 0000-0001-6545-7181   +4 more
openaire   +3 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

PENGUASAAN KONSEP DAN KETERAMPILAN PEMECAHAN MASALAH SETELAH DIAJARKAN DENGAN PENDEKATAN KETERAMPILAN PROSES

open access: yesJurnal Bidang Pendidikan Dasar, 2017
Abstrak   Tujuan penelitian ini adalah untuk mendeskripsikan penguasaan konsep siswa dan keterampilan pemecahan masalah melalui Pendekatan Keterampilan Proses.
Arnelia Dwi Yasa
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

A cross-cultural study of High School teachers’ tacit knowledge of interpersonal skills [PDF]

open access: yes, 2018
Effective teachers are characterized not only by pedagogical abilities and subject area mastery, but also by interpersonal skills. Using the Tacit Knowledge Inventory for High School Teachers (TKI-HS) – a situational judgement test consisting of 11 ...
Elliott, Julian   +5 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Pengaruh Representasi Analogi Terhadap Kemampuan Berpikir Rasional Dan Penguasaan Konsep Fisika Siswa [PDF]

open access: yes, 2013
This research that aims to know the influence of: Analogy representation toward students’ rational thinking ability, and students’ mastery of Physics concept. The research used one class as sample i.e. class X2 that consisted of 27 students. One-shot
Fidianingsih, R. (Rista)   +2 more
core  

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