Results 121 to 130 of about 348,254 (301)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Identification of Students' Mastery Level of Physics Concepts in Static Fluid Material

JPFT (Jurnal Pendidikan Fisika dan Teknologi)
This study aims to identify the level of mastery of physics concepts on static fluid material. This research uses quantitative descriptive methods. The research subjects consisted of 23 MA students in Malang.
Fatmawati Liana Wulandari, Parno Parno, Markus Diantoro   +2 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

PENINGKATAN PENGUASAAN KONSEP DAN EFIKASI DIRI SISWA SMA MELALUI MODEL PROCESS ORIENTED GUIDED INQUIRY LEARNING (POGIL) PADA KONSEP PEMBUATANKOLOID [PDF]

, 2016
Penelitian ini bertujuan untuk menganalisis peningkatan penguasaan konsep dan efikasi diri siswa melalui pembelajaran POGIL pada konsep pembuatan koloid.
Oktarina, Hidayati
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

E-Modules Based on Contextual Wetlands to Improve Mastery of Physics Concepts of High School Students

JPFT (Jurnal Pendidikan Fisika dan Teknologi)
E-modules based on the wetland context represent one of the alternative teaching materials that can support the learning process. This study aims to develop a physics e-module contextualized with wetlands using Adobe Captivate software, with the goal of
Betty Lusiana, Apit Fathurohman, Kistiono Kistiono   +2 more
doaj   +1 more source

PENERAPAN PENDEKATAN SAINTIFIK DENGAN BERBANTUAN PROTOTYPE MEDIA BERBASIS CMAP TOOLS UNTUK MENINGKATKAN PENGUASAAN KONSEP SISWA SMA [PDF]

, 2015
Penguasaan konsep penting dimiliki siswa karena penguasaan kosep mampu meningkatkan kemampuan intelektual siswa. Penguasaan konsep adalah kemampuan mengenai pengetahuan terkait suatu konsep dan penggunaannya untuk menyelesaikan persoalan-persoalan ...
Fauziah, Adilla
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

PROFIL PENGUASAAN KONSEP SISWA SMK PADA MATERI GERAK ROTASI DAN KESEIMBANGAN BENDA TEGAR MELALUI PETA KONSEP [PDF]

, 2016
Profil Penguasaan Konsep Siswa SMK Melalui Peta Konsep pada materi Keseimbangan Benda Tegar ini bertujuan untuk memperoleh gambaran umum penguasaan konsep yang dimiliki siswa SMK pada konsep keseimbangan benda tegar.Penilaian terhadap peta Konsep siswa
Meitania, Tri
core