Results 51 to 60 of about 22,151 (256)

The Validity of Android-Based Biology Teaching Materials to Improve Students' Concept Mastery

open access: yesPrisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram, 2021
This study aims to develop appropriate android-based teaching materials to improve students' mastery of concepts. This study is a qualitative descriptive study to assess and obtain the quality of a valid android-based learning material knowledge ...
Kurnia Dewi Rusdiana Putri   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Helping students demonstrate mastery of doctoral Threshold Concepts [PDF]

open access: yes, 2017
Research into the characteristics of successful PhD theses (See for example Bourke, Hattie, & Anderson, 2004; Holbrook & Bourke, 2004; Kiley & Mullins, 2004; Lovitts, 2007; Mullins & Kiley, 2002) suggests that examiners expect to see evidence of a variety of relatively abstract rather daunting achievements and skills.
Wisker, Gina, Kiley, Margaret
openaire   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

PENGEMBANGAN PERANGKAT PEMBELAJARAN FISIKA KESEHATAN BERBASIS MASALAH UNTUK MENINGKATKAN PENALARAN DAN PENGUASAAN KONSEP MAHASISWA KEBIDANAN

open access: yesJurnal Pendidikan Fisika Indonesia, 2013
ABSTRAKPenelitian ini bertujuan untuk mengembangkan perangkat pembelajaran fisika kesehatan berbasis masalah yang valid dan efektif. Perangkat pembelajaran ini dikembangkan dengan mengacu pada model pengembangan  Borg dan Gall. Objek penelitian dilakukan
A. Fahkrudin, Hartono -, Sutikno -
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Pengaruh Cooperative Meaningful Instructional Design (C-MID) Berbantuan Multimedia Interaktif Terhadap Penguasaan Konsep Fisika Peserta Didik

open access: yesJPFT (Jurnal Pendidikan Fisika dan Teknologi), 2020
This research aimed to examine the effect of cooperative meaningful instructional design assisted interactive multimedia for students’ physics concept mastery.
Al Qoni'ah   +2 more
doaj   +1 more source

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