Results 111 to 120 of about 2,853,998 (305)
The Examination of Organizational Respect in Relation to Organizational Culture [PDF]
, 2014 This paper is an in-depth examination of the connection between organizational respect and the strong roots of organizational culture. Throughout this thesis, we will examine the importance of management recognizing and implementing respect, how respect ...
Walker, Amanda N
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Management of Health System for Ethnic Minorities [PDF]
The concept of ethnic minority refers to a different ethnic group, living in a residential country, with a different birth place and ethnic membership, different language, religion and citizenship, and different culture.
Cristina Teodora NEAGU
core
Educational values, intrinsic or extrinsic : a study of parent pupil preferences : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Education at Massey University [PDF]
, 1975 A perennial problem faced by teachers, administrators and educational researchers is that of improving the performance levels of high school pupils. Efforts to understand some of the factors which contribute to scholastic achievement have established ...
Panny, Carol Constance
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Steps towards operationalizing an evolutionary archaeological definition of culture [PDF]
, 2011 This paper will examine the definition of archaeological cultures/techno-complexes from an evolutionary perspective, in which culture is defined as a system of social information transmission.
Riede, F
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source