Results 41 to 50 of about 562,483 (308)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
The Concept of Security in Turkish History and Culture
Концепт: философия, религия, культура, 2023 An analysis of the evolution of academic approaches to security issues in Turkish politics will help shed light on the development of Turkish political thought and the main theories and ideas that served as a catalyst for this process.
S. A. Davydov
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Henrique Vaz, Darwin and Cassirer: Being Human and Transcendence
Open Theology, 2018 This article compares the approach of the Brazilian philosopher Henrique Vaz to the ones of Charles Darwin and Ernst Cassirer about human nature. Firstly, the text expounds Darwin’s ideas about human species in his The Descent of Man and Selection in ...
Portugal Agnaldo
doaj +1 more source
Is the Concept of Animal Welfare Incompatible with Chinese Culture?
, 2020 In discussions about nonhuman animal protection in China in recent years, one consistent theme is many people in China believe that animal welfare and the legal protection of animals are ahead of their time, and that animal welfare is a Western concept ...
Cao, Deborah
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Multilingual arts and culture intermediate phase terminology list [PDF]
, 2015 Department of Arts and Culture: Republic of South AfricaThe main purpose of this terminology list is to promote better communication between learners and teachers and to educate the general public.
Department of Arts and Culture
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