Results 51 to 60 of about 2,853,998 (305)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Henrique Vaz, Darwin and Cassirer: Being Human and Transcendence

open access: yesOpen Theology, 2018
This article compares the approach of the Brazilian philosopher Henrique Vaz to the ones of Charles Darwin and Ernst Cassirer about human nature. Firstly, the text expounds Darwin’s ideas about human species in his The Descent of Man and Selection in ...
Portugal Agnaldo
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Concept of 'bad death' in language and culture

open access: yesEtnoantropološki Problemi, 2014
Following previous research on the linguistic concept of а 'bad death' which lexical expression is the word family of the verb ginuti, I focus my attention in this paper on the relationship between language conceptualization of а 'bad death' and the ...
Marija Vučković
doaj   +1 more source

Cultural issues, organisational hierarchy and information fulfilment: an exploration of relationships [PDF]

open access: yes, 2007
Purpose – The purpose of this paper is to present the cultural results of a three year study into the concept of information fulfilment and considers the impact of culture on levels of information fulfilment.
Burke, ME
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Extralinguistic corelation between the concept of culture and tourism [PDF]

open access: yesJournal of Social Sciences, 2019
This article describes the concept of culture that includes knowledge, traditions, words, abstract norms, religion and other aspects of a nation. Сulturаl tоurism inсludes alive аnd аrtistiс fоrms оf humаn expressiоn referred tо аs аrts аlоng with ...
IVANIUC, Corina
doaj   +1 more source

Mathematics Learning Within Culture And Nation Character: Using Traditional Dance In Learning The Concept Of Symmetry At Grade IV Primary School [PDF]

open access: yes, 2011
This paper introduces a new approach in mathematics learning within culture and nation character. Indonesian traditional dances are used as a context in learning the concept of symmetry.
Yullys , Helsa, Yusuf , Hartono
core  

Trust-based quality culture conceptual model for higher education institutions [PDF]

open access: yes, 2018
Higher Education Institutions (HEIs) play a crucial role in societies as they enhance the sustainable development of nations. In a context of increasing competition and financial difficulties in higher education institutions, the loyalty of students ...
Dzimińska, Małgorzata   +2 more
core   +1 more source

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