Results 71 to 80 of about 562,483 (308)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2018 Sports often serve as a microcosm for culture and society, and thus when meanings surrounding sports are disrupted, it likely represents a larger disruption of cultural and societal meanings, as well as group and individual identities.
core
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2019 In a play of divided lands and language, Sarah John Sally in Brian Friel’s Translations presents a unique bifurcation; somewhere between character and caricature, aisling and invalid, the actor performing Sarah must tread a delicate balance between ...
core
Applications of Education Games Based Local Culture to Increase the Ability the Concept of Numbers [PDF]
, 2017 This study aims to find out the application of Education Games application based on local culture in improving the ability to recognize the concept of numbers in children in PAUD Melati DWP UNM.
Sirajuddin, Saleh +2 more
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Liang Shuming’s Concept of Culture: The Chinese Way
Концепт: философия, религия, культураThe article is devoted to the analysis of the discussions around the theory of cultural interactions by Chinese philosopher Liang Shuming. The teaching was formed in the 1920s in the framework of New Culture Movement and resonated both with ...
Gao Qing, M. N. Fomina
doaj +1 more source
Littleness of the Culture in the Middle Europe for Example Slovensko a jeho život literárny (Slovakia and Her Literary Life) by Jozef Miloslav Hurban ). [PDF]
Slovenska Literatura, 2005 “Littleness” appears as relevant for certain culture when it is determined by its own or foreign texts. This determination in an intercultural contact behaves as an explicit or implicit valuing act approached within the positions of superiority ...
CHRISTIAN PRUNITSCH
doaj