Results 81 to 90 of about 562,483 (308)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The Process and Implications of Self-Stigma in Schizophrenia
, 2014 Despite increased understanding of the diagnosis and treatment of mental health disorders, misperceptions about these disorders persist, leading to stigma and discrimination toward those who live with them. For the purposes of this article, stigma refers
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This volume introduces a new concept that boldly breaks through the traditional dichotomy of high and low culture while offering a fresh approach to both: unpopular culture.
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Dr. No and Dr. Strangelove: Cold War Anxiety in Film, 1962-1964*
, 2014 The early 1960s saw a string of popular Cold War spy movies and television shows that illuminated the complexities of life in Cold War America. Movies like Ian Fleming’s Dr.
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
THE ENTERPRENEURIAL UNIVERSITY: CONCEPT AND DIAGNOSIS OF CULTURE
Вестник Мининского университета, 2017 This article analyses the concept of entrepreneurial university and the role of culture in its formation. The problem of appropriate diagnostic method is being risen.
G. A. Mkrtychyan
doaj +2 more sources
Encyclopedia of Tuvan culture: timeliness, concept, problems
Новые исследования Тувы, 2016 Article arises the problem of creating the encyclopedia of Tuvan culture. History of development of encyclopedia projects in world culture is reviews as well as description of the variants of encyclopedias in 20th century. Characteristics of dictionaries
Chimiza K. Lamazhaa
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Continuity in the Concept: A Concept Analysis of Quality Culture in Complex Adaptive Systems
Vietnam Journal of Education, 2023 In this article we define the concept of quality culture in a complex higher education context. The article aims to start a creative dialogue on the conceptual continuity of the concept of quality culture in the form of a literature review.
Everard van Kemenade
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