Results 161 to 170 of about 299,575 (258)

Research on the process planning and multi-method integration strategy of product conceptual design with cognitive mechanisms. [PDF]

Sci Prog, 2021
Yan-Jian W, Jun W, Yong-Wei W, Xin-Fa D, Sheng-Long X, Zi-Liang C.   +5 more
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Conceptual design of airborne contra rotating VAWTs for rooftop wind energy. [PDF]

Sci Rep
Radhakrishnan J, Sridhar S, Zuber M, Ng EYK, Shenoy BS.   +4 more
europepmc   +1 more source

Conceptual design of a health suit to prevent COVID-19 and similar type other airborne virus infections. [PDF]

Med Devices Sens, 2021
Sinha S, Sinha S, Sinha S, Manna B.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Conceptual design of the energy-switchable storage ring as a high-brilliance light source over a wide wavelength range. [PDF]

J Synchrotron Radiat
Sato T, Funamori N, Amemiya K, Usami N, Ohigashi T, Kataoka R, Shimizu N, Tanaka H, Nakao H, Yamada Y, Wakabayashi D, Obina T, Adachi M, Kobayashi Y, Shimosaki Y, Tanimoto Y, Tsuchiya K, Harada K, Yamamoto N, Igarashi N.   +19 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Preserving conceptual design integrity: strategies for enhancing interoperability in architectural digital design workflows. [PDF]

Sci Rep
El-Khouly T, Abdelhalim O.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Conceptual design of a decision knowledge service model integrating a multi-agent supply relationship diagram for electric power emergency equipment. [PDF]

Front Big Data
Si J, Liu C, Ye J, Wu J, Wang J, Hu K, Ju C, Cao Q.   +7 more
europepmc   +1 more source