Results 151 to 160 of about 299,575 (258)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Conceptual Design of a Hybrid Composite to Metal Joint for Naval Vessels Applications. [PDF]

Materials (Basel)
Cheung MC, Djordjevic N, Worrall C, Vignjevic R, Kazilas M, Hughes K.   +5 more
europepmc   +1 more source

Realization of user-friendly bioanalytical tools to quantify and monitor critical components in bio-industrial processes through conceptual design. [PDF]

Eng Life Sci, 2022
Mandenius CF.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

A New Conceptual Design of Twisting Morphing Wing. [PDF]

Biomimetics (Basel)
Kumkam N, Suratemeekul N, Sleesongsom S.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Metastructure-enabled scalable multiple mode-order converters: conceptual design and demonstration in direct-access add/drop multiplexing systems. [PDF]

Nanophotonics
Guo Z, Zhao W, Wu S, Lai Y, Cheng S, Dai D.   +5 more
europepmc   +1 more source

In Situ Printing and Functionalization of Hybrid Polymer-Ceramic Composites Using a Commercial 3D Printer and Dielectrophoresis-A Novel Conceptual Design. [PDF]

Polymers (Basel), 2021
Tselikos G, Rasul S, Groen P, Li C, Khaliq J.   +4 more
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Investigating the needs of older adults with type 2 diabetes and conceptualizing a healthy diet management application: a conceptual design. [PDF]

BMC Geriatr
Li J, Me RC, Fakhruddin NNINM, Ahmad FA, Zhu Q.   +4 more
europepmc   +1 more source