Results 211 to 220 of about 2,244,720 (326)

Conceptual Design of a Near-Zero Emission and Cost-Efficient Regional Air Mobility Solution

, 2020
David Eržen, Fabrizio Oliviero, Lorenzo Trainelli   +2 more
openalex   +1 more source

A Model for Creating Cadidates for Conceptual Design

, 1995
Fuminori IKEMOTO, Hirosi Kawakami, Tadataka KONISHI   +2 more
openalex   +2 more sources

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Preserving conceptual design integrity: strategies for enhancing interoperability in architectural digital design workflows. [PDF]

Sci Rep
El-Khouly T, Abdelhalim O.
europepmc   +1 more source

Conceptual design and thermodynamic optimization of a novel composition tunable zeotropic organic Rankine cycle

, 2019
Chaonan Chen, R. Q. Huang, Xianglong Luo, Jianyong Chen, Zhi Yang, Ying Chen   +5 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Conceptual design of a decision knowledge service model integrating a multi-agent supply relationship diagram for electric power emergency equipment. [PDF]

Front Big Data
Si J, Liu C, Ye J, Wu J, Wang J, Hu K, Ju C, Cao Q.   +7 more
europepmc   +1 more source

Interactive freehand sketching as the means for online communication of design intent in conceptual design conducted by Brainwriting. [PDF]

Int J Interact Des Manuf, 2021
Rizzuti S, De Napoli L.
europepmc   +1 more source

Modularization Method Based on New Layout Design in Conceptual Design Stage - Application of Multi-material Lightweight Structures Utilizing Machine Learning

, 2019
Yasuo ASAGA, Hidekazu NISHIGAKI, Hidekazu Nishigaki   +2 more
openalex   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source