Results 21 to 30 of about 270,662 (239)

Automated Optimal Motion Sequence of a 9-Bar Linkage

Frontiers in Built Environment, 2020
Automated optimization-driven analyses may lead to an emersion of innovative design approaches, while investigating the potentials in design, analysis and control of high-performance engineering structures, and adaptive architecture. In the present study,
Maria Matheou, Nikos A. Kallioras, Nikos D. Lagaros, Marios C. Phocas   +3 more
doaj   +1 more source

Surrogate-Based Optimization Design for Air-Launched Vehicle Using Iterative Terminal Guidance

Aerospace, 2022
In recent years, the penetration of low-cost air-launched vehicles for nano/micro satellites has significantly increased worldwide. Conceptual design and overall parameters optimization of the air-launched vehicle has become an exigent task.
Jiaxin Li, Donghui Wang, Weihua Zhang
doaj   +1 more source

Investigations of the Fire Behavior of Functionally Graded Concrete Slabs with Mineral Hollow Spheres

Fire
Functionally Graded Concrete (FGC) allows for a significant reduction in the mass of concrete components while maintaining their structural and functional requirements and improving recycling capacity.
Benedikt Strahm, Carl Niklas Haufe, Lucio Blandini   +2 more
doaj   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Materials Selection in Conceptual Design using Weighting Property Method [PDF]

Engineering and Technology Journal, 2011
The needs to combine selection of materials (SM) processes during the early stages of design have previously been realized. In this work, an attempt is made to ensure that there is no gap between function oriented design and the material.
Suad Hamzah Abdas, Mithal A. Al-Bassam, Mohammed Jasim Kadhim   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Multi-criteria performance assessment of an adaptive kinetic photovoltaic shading system

Frontiers in Built Environment
This paper presents a multi-criteria performance assessment of KineticSKIN, a climate-responsive adaptive façade system that integrates thin-film photovoltaic shading devices into bifurcated folding modules.
Ana Caroline Ghidini, Doris Österreicher, Maria Matheou   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source