Results 41 to 50 of about 329,719 (257)
Creative Decision-Making Processes in Parametric Design
Buildings, 2020 Decision-making in design is a cognitive process wherein alternatives are generated and evaluated, potentially enabling a more creative design process.
Ju Hyun Lee, Michael J. Ostwald
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Abstraction in conceptual model design [PDF]
International Journal of Human-Computer Studies, 1997 Abstract Understanding and supporting conceptual model design is an important issue in Model Management System (MMS) research. While there are a broad range of aspects which affect conceptual design, this study focuses on the use and the support of abstraction in the design process.
Diana Kao, Norman P. Archer
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Investigating of the Leap Required in Effective Technologies for SSTO Design Using MDO [PDF]
فصلنامه علوم و فناوری فضاییThe possibility of injecting a satellite into orbit using a single-stage carrier has been one of the challenges far from human hands since the past. Even in the past, to prove the impossibility of achieving this wish, various mathematical relations and ...
Fatemeh Ghorbani +3 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Adaptive high-performance and multifunctional façade systems
Frontiers in Built EnvironmentAdaptive, high-performance and multifunctional façades are recognized as key contributors to the EU’s climate-neutral agenda, as outlined in Directive (EU) 2024/1275, the Renovation Wave, and Horizon Europe initiatives.
Maria Matheou +3 more
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Evaluating the Impact of Design Changes in Remote Sensing Satellites Using Design Structure Matrix [PDF]
فصلنامه علوم و فناوری فضاییDesigning complex systems, especially in the space industry, is accompanied by challenges such as changes in components and their interactions. This article aims to facilitate the design of complex systems by introducing and examining the design ...
Mohammad Sayanjali
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Applied Sciences, 2020 The use of wood in the construction of bridges has increased in recent decades thanks to the characteristics of this material, i.e., environmentally-friendly and suitability within natural landscapes. Nevertheless, timber constructions may be affected by
Alessandra Fiore +2 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source