Results 111 to 120 of about 2,241,486 (282)

Family and Store Choice - A Conceptual Framework [PDF]

Retail Store choice has traditionally been studied from the perspective of an individual. The retail offering is however consumed more by the family than by an individual.
Sinha, Piyush Kumar, Sinha, Piyush Kumar, Tripathi Sanjeev   +2 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

An Object-Oriented Framework for Explicit-State Model Checking [PDF]

, 2007
This paper presents a conceptual architecture for an object-oriented framework to support the development of formal verification tools (i.e. model checkers).
Kattenbelt, M., Rensink, A., Ruys, T.C.
core   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Difference games and policy evaluation: A conceptual framework [PDF]

Economics
Ploeg, F. van der, Zeeuw, A.J. de
core   +4 more sources

The Economics of Solidarity: A Conceptual Framework [PDF]

For many people "solidarity" has become a meaningless word used in slogans - too often used without leading to any economic consequences. We show in this paper conditions under which solidarity can be a powerful instrument.
Bolle, Friedel, Kritikos, Alexander S., Tan, Jonathan H. W.   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Exploring rodent prosociality: A conceptual framework

Translational Neuroscience
Prosociality is a behavior characterized by actions performed for the benefit or well-being of others. Recent studies have corroborated parallels in brain activation patterns between rodents and humans during prosocial behaviors.
Charron Valérie, Talbot Joey, Plamondon Hélène   +2 more
doaj   +1 more source

HEALTH AND HEALTH ECONOMICS: A CONCEPTUAL FRAMEWORK [PDF]

Over the last three decades, treating health economics as an independent scientific discipline and providing specific treatment to the topics related to the economics of the health care sector have become more and more common.
Himanshu Sekhar, Rout, Narayan C handra, Nayak   +1 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source