Results 41 to 50 of about 4,340,597 (294)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk   +10 more
wiley   +1 more source

Intertextual meme “One does not simply”: conceptual blending diagrams

open access: yesКогниция, коммуникация, дискурс
The article aims to expand the analytical and explanatory potential of the theory of intertextuality by applying the principles and methodology of cognitive-discursive linguistics to take into account the cognitive mechanisms of establishing intertextual
Olena Nefyodova
doaj   +1 more source

Conceptual tools for the integration of data

open access: yesComptes Rendus. Biologies, 2002
We propose to start the analysis of complex systems by systematically identifying the feedback circuits that govern their dynamics. These circuits can be identified without any ambiguity by examining the Jacobian matrix of the system. They provide precious information regarding the number and nature of steady states.
Thomas, René, Kaufman, Marcelle
openaire   +4 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Grammatical Conceptualization as a Poetic Strategy in E. E. Cummings' yes is a pleasant country

open access: yesMiscelánea: A Journal of English and American Studies, 2003
This article applies the theoretical principles of cognitive linguistics to E.E. Cummings’ poetic composition yes is a pleasant country. It combines the perspectives of conceptual metaphor theory, blending theory and the conceptual integration network ...
Pilar Alonso Rodríguez
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fit in the Body: Matching Embodied Cognition with Social-Ecological Systems

open access: yesEcology and Society, 2012
Analysis of fit has focused on the macrolevel fit between social institutions and ecosystems, and bypassed the microlevel fit between individual cognition and its socio-material environment.
Janne I. Hukkinen
doaj   +1 more source

Integrating GIS and FEATHERS: A Conceptual Design

open access: yesProcedia Computer Science, 2014
AbstractThis study proposes integrating GIS and FEATHERS in order to improve the capability of data management, spatial analysis and visualization in the model framework. GIS provides geodatabase for effectively storing and edit (non-)spatial data, useful functions of spatial analysis for defining spatial interactions between phenomena simulated by the
Sungjin Cho   +3 more
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Social Media Use and Social Integration of Ethnic Minorities in Germany: A New Interdisciplinary Framework [PDF]

open access: yesAthens Journal of Mass Media and Communications, 2016
Faced with an increasingly diverse society, Germany is challenged with the integration of different ethnic minorities. Previous studies have shown that mass media can play a crucial role in the integration process.
Alexandra Mittelstädt, Özen Odag
doaj   +1 more source

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