Results 71 to 80 of about 4,340,597 (294)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Дискурс профессиональной коммуникацииVerbal and visual metaphorical and metonymic images are key instruments of political satire, enabling the concise and expressive conveyance of evaluative attitudes toward socio-political realities.
S. Y. Pavlina, N. G. Milashchenko
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Інформаційні технології і засоби навчання, 2018 In the XXI century, the age of information technologies, traditional boarders between disciplines and subjects are being erased. This process gives the floor for new sciences to appear which integrate the qualities of several traditional for XX century ...
Liliya I. Morska +3 more
doaj
Visual–verbal blending in social advertising: Conceptual integration and meaning compression in environmental and humanitarian campaigns [PDF]
Training, Language and CultureThis study examines visual–verbal blending as a mechanism through which social advertising compresses complex environmental and humanitarian problems into concise multimodal messages.
Aida Nurbayeva +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Teaching Fables in the Junior Grades of Primary School [PDF]
Revija za Elementarno Izobraževanje, 2015 The aim of this paper is to explore the ways in which fables can help pupils in the junior grades of primary school develop their oral and written skills.
Ester Vidović, Emilija Reljac Fajs
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Smartcard Integration with Kerberos V5 [PDF]
, 1998 We describe our design and implementation of smartcard integration with Kerberos V5. Authentication is among the most important applications for smartcards and is one of the critical requirements for computer security.
Itoi, Naomaru, Honeyman, Peter
core +4 more sources