Results 171 to 180 of about 3,563,997 (305)
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
CONCEPTUAL FRAMEWORK FOR XML SCHEMA MAPPING
, 2008 Aujourd'hui, les applications et les services Web publient leurs données à l'aide de XML, car cela favorise l'interopérabilité avec d'autres applications et services. L'hétérogénéité des données XML a conduit à des recherches récentes sur la correspondance des schémas, la transformation des schémas et l'intégration des schémas XML.
Lamolle, Myriam +2 more
openaire +2 more sources
Lesser Sunda Islands 1:250,000 /
, 1943 Various editions. Topographic map series of Lesser Sunda Islands, Indonesia. Five classes of roads and trails, various types of air fields, and two types of internal boundaries are shown.; Elevations are shown by hachures or contours, and spot heights ...
United States. Army Map Service, cartographer.
core
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Tokyo and vicinity [cartographic material] : showing bombed-out areas /
, 1946 Town plan of Tokyo showing administrative and municipal boundaries, transportation, water features, religious, public and government buildings, built-up areas and sub-divisions of the chome.
Nippon Map (Firm)
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Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
An Ontology for the Adoption of Medical Devices in Health Care Organizations: Design and Development Study. [PDF]
J Med Internet ResVannelli S, Spoladore D, Visintin F.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source