Results 241 to 250 of about 3,563,997 (305)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Conceptualization, Contexts, and Measurement of Nursing Theoretical Literacy: Protocol for a Scoping Review. [PDF]

JMIR Res Protoc
Ge J, Song H, Yang J, Feng Y, Zheng T, Wang M, You M, Peng S.   +7 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Mechanistic Perspectives From Genomics and Pangenomics of Medicinal and Aromatic Plants: Linking Genome Architecture to Phytochemical Diversity. [PDF]

Int J Genomics
Saini H, Yadav J, Johar V, Vyas S, Jaryan V, Kumar A, Nanda D, Kumar A, Kaushik JJ, Shamkuwar S, Singh S.   +10 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

How the Camel's Back Breaks: A Scoping Review of Cumulative Occupational Distress and the Conceptual Absence of Micro-Trauma in Nursing. [PDF]

Nurs Rep
Dale M, Chapman M, West C.
europepmc   +1 more source

Artificial Intelligence for Perioperative Risk Prediction in Anesthesiology: A Bibliometric and Knowledge-Mapping Analysis. [PDF]

Healthcare (Basel)
Özkılıç M.
europepmc   +1 more source

From Tool to Social Actor: A Systematic Review of the Psychological Mechanisms Through Which Conversational AI Reshapes the Employee Experience. [PDF]

Behav Sci (Basel)
Liu L, Zhang R, Su X.
europepmc   +1 more source

Knowledge Mapping of Human Genetic Variation in Multiomics Biomarker Translation: A Bibliometric Analysis. [PDF]

Hum Mutat
Zhao B, Ran W, Liang N.
europepmc   +1 more source