The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley +1 more source
A Conceptual Model for Understanding the Division and Transfer of Diabetes Care Responsibilities Between Parents and Children with Type 1 Diabetes. [PDF]
Aalders J, Pouwer F, Hartman E, Nefs G.
europepmc +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Co-designing a Vaping Cessation Program for Australian Young Adults: A Conceptual Model. [PDF]
Rahman N, Sebar B, Sofija E.
europepmc +1 more source
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Parental and individual determinants of dental trust in children: a path analysis of a conceptual model. [PDF]
Taskaya B, Buldur B.
europepmc +1 more source
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti+5 more
wiley +1 more source
A conceptual model and practical guidance for the development, administration, and evaluation of individualized therapies. [PDF]
Perillat L+3 more
europepmc +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
Coordinated empathy in attending general practitioners: an interpretive phenomenological approach to constructing a conceptual model of empathy. [PDF]
Muramatsu E+4 more
europepmc +1 more source