Results 131 to 140 of about 2,581,054 (298)
Presenting of change management model for copper industries with HSE approach using FAHP and DEMATEL
Salāmat-i kār-i Īrān, 2020 Background and Aims: management of change is one of the requirements of quality standards in dynamic industries. Make changes without evaluation can be a challenge, if not managed properly, can be irreparable damage.
Manouchehr Omidvari +2 more
doaj
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Semantic and pragmatic interoperability: a model for understanding [PDF]
, 2005 In this paper we present a conceptual model for understanding of semantic and pragmatic interoperability.
Pokraev, S.V. +3 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Explaining the Effects of Climate Elements in Tehran’s Metropolis Air Quality
تحقيقات جغرافيايی, 2018 Introduction and Background Atmospheric pollutants are elements whose high concentrations cause damage to the Earth’s biological cycles, and its concentration is usually determined by concentrations of air pollutants such as nitrogen dioxide, sulfur ...
nabi allah ramezani +2 more
doaj
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Assessing the Quality of Public Services: A Conceptual Model [PDF]
One of the major challenges faced by Public Administration is how to create more value for both citizens and firms, mainly because of the increasing budgetary constraints and challenging demands from society.
Carlos Brito +2 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Changing Agricultural Marketing Channel Structures: Interdependences & Risk Preferences [PDF]
We propose a conceptual model that integrates transaction cost and risk behavior theories in an interdependence framework. Hypotheses are offered that relate the concepts that are central to the proposed model to the three dimensions of channel ...
Franken, Jason R.V. +1 more
core +1 more source