Results 131 to 140 of about 557,360 (315)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Conceptual model evaluation. Towards more paradigmatic rigor [PDF]
, 2005 Information Systems (IS) research has so far been primarily concerned with the development of new modeling languages, techniques, and methods. Also, evaluation approaches have been developed in order to assess the appropriateness of a modeling approach ...
Recker, Jan C.
core
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Presenting of change management model for copper industries with HSE approach using FAHP and DEMATEL
Salāmat-i kār-i Īrān, 2020 Background and Aims: management of change is one of the requirements of quality standards in dynamic industries. Make changes without evaluation can be a challenge, if not managed properly, can be irreparable damage.
Manouchehr Omidvari +2 more
doaj
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
A conceptual model and rapid appraisal tool for integrated coastal floodplain assessments [PDF]
, 2014 Low-lying coastal zones are high-risk areas threatened by flooding due to extreme coastal events and rising sea-levels. The coastal floodplain system includes elements such as near-shore waves and water levels, inter-tidal beaches and coastal habitats ...
Narayan, S.
core
The notion of role in conceptual modeling
, 1997 Dates de conf{\'e}rence : octobre 1997 ...
Chantal Reynaud +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source