FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
A new conceptual model for seed germination and seedling tillering of winter wheat in the field. [PDF]
R Soc Open SciChen J +5 more
europepmc +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
A systematic review of the blockchain application in healthcare research domain: toward a unified conceptual model. [PDF]
Med Biol Eng ComputCihan S, Yılmaz N, Ozsoy A, Beyan OD.
europepmc +1 more source
White Christian Nationalism in the Rural United States
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Many scholars have sought to link the rise of right‐wing populist movements, like White Christian Nationalism (WCN), to the impacts of political‐economic structural changes, such as globalization and financialization. Although these structural changes may explain some grievances, they do not explain why people express those grievances in the ...
Leland L. Glenna
wiley +1 more source
Caregiver factors influencing family-based treatment for child and adolescent eating disorders: a systematic review and conceptual model. [PDF]
PeerJMcCord A, Rice K, Rock A.
europepmc +1 more source
White Christian Nationalism: Adult Education and Threats to Democracy
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Adult education has a historical and ongoing commitment to fostering democratic relationships, demonstrated by the tendency of adult education to be called upon when social change and realignment are most desirable. This article considers the philosophical and pragmatic possibilities for adult education at this moment, when White Christian ...
Ralf St. Clair, Lyn Tett, Rob Black
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT Since the January 2021 attack on the US Capitol, the influence of White Christian nationalism (WCN) has become even more pronounced and concerning. Adult educators and the public need a better understanding of whether and how WCN can be unlearned, and the roles ordinary citizens and adult educators can play in this process.
Esther Prins
wiley +1 more source
Housing insecurity pathways to physiological and epigenetic manifestations of health among aging adults: a conceptual model. [PDF]
Front Public HealthBhat AC, Fenelon A, Almeida DM.
europepmc +1 more source
Co-creating a conceptual model of Indigenous relational wellbeing in early childhood: Planting seeds of connectedness. [PDF]
Infant Ment Health JWesner CA +11 more
europepmc +1 more source