Results 41 to 50 of about 103,754 (266)
A Conceptual Model for Born-Accessible Web Accessibility Regeneration Using Large Language Models
ComputersWeb accessibility remediation using large language models (LLM) has recently gained attention; however, most approaches remain tool-centric and lack formal architectural grounding.
Guillermo Vera-Amaro +1 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
Selected Topics on Business Informatics Research: Introduction to Issue 21 of CSIMQ
Complex Systems Informatics and Modeling Quarterly, 2019 This issue of the journal on Complex Systems Informatics and Modeling Quarterly contains publications that present extended papers from the workshops of the 18th International Conference on Perspectives in Business Informatics Research (BIR 2019 ...
Raimundas Matulevičius, Václav Řepa
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
International Journal of Computing, 2014 Decision making is mostly based on decision concepts and decision models built in decision support systems. Type of decision problem determines application. This paper presents a conceptual decision model that utilises rule- based methodologies, numerical algorithms and procedures, statistical methodologies including distributions, and visual support ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A survey on the model-centered approaches to conceptual modeling of IoT systems
Frontiers in Computer Science, 2023 Internet of Things (IoT) is a system of connected objects, entities, devices, and components which share and transfer data over a network. Many papers are published on the topic of conceptual models in the IoT context, but it is difficult to assess the ...
Sofia Kohan +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source