Results 51 to 60 of about 103,754 (266)

Un modelo multidimensional conceptual espacio-temporal A conceptual spatio-temporal multidimensional model

Revista Ingenierías Universidad de Medellín, 2010
Hoy, gracias a los sistemas de posicionamiento global y dispositivos móviles equipados con sensores de rastreo, se puede recopilar una gran cantidad de datos sobre objetos móviles, es decir, datos espacio-temporales relacionados con el movimiento seguido
Francisco Moreno, Jaime Alberto Echeverri Arias, Bell Manrique Losada   +2 more
doaj  

Addressing complexity and uncertainty: conceptual models and expert judgments applied to migratory birds in the oil sands of Canada

Ecology and Society, 2015
Complexity and uncertainty are inherent in social-ecological systems. Although they can create challenges for scientists and decision makers, they cannot be a reason for delaying decision making.
Marc A. Nelitz, Ben Beardmore, Craig S. Machtans, Alexander W. Hall, Chris Wedeles   +4 more
doaj   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos, Lindsay A. Jibb, Gary Rodin   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

CSIMQ Anniversary Editor-in-Chief Thoughts and Editorial Introduction to Issue 38: Model-based and Decision Support Methods for Next-generation Information Systems

Complex Systems Informatics and Modeling Quarterly
The 38th issue of CSIMQ comprises four articles selected by guest issue editors on topics related to novel decision support methods or model-based frameworks for evolving or evaluating information systems.
Anders Flodström, Robert Andrei Buchmann, Andrea Morichetta   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

A TERNARY CONCEPTUAL FRAMEWORK OF CRITICAL INFRASTRUCTURE RESILIENCE MANAGEMENT CYCLE

Надежность и качество сложных систем
Background. The study considers hot-button issues of analysis and modeling of the critical infrastructure resilience cycle in order to engineering automated tools for management information support of the resilient functioning of these complex ...
A.V. Masloboev
doaj   +1 more source

A conceptual spatio-temporal multidimensional model

Revista Ingenierías Universidad de Medellín, 2011
Today, thanks to global positioning systems technologies and mobile devices equipped with tracking sensors, and a lot of data about moving objects can be collected, e.g., spatio-temporal data related to the movement followed by objects.
Francisco Moreno, Jaime Alberto Echeverri Arias, Bell Manrique Losada   +2 more
doaj