Results 181 to 190 of about 366,121 (313)

Feedback Loops in Conceptual Models of Land Change: Lost in Complexity?

Ecology and Society, 2011
Anna M. Hersperger, Maria-Pia Gennaio, Peter H. Verburg, Matthias Bürgi   +3 more
doaj   +1 more source

Conceptual Models of Food Choice: Influential Factors Related to Foods, Individual Differences, and Society. [PDF]

Foods, 2020
Chen PJ, Antonelli M.
europepmc   +1 more source

A perspective and framework for the conceptual modelling of knowledge

, 2012
Conceptual modelling of knowledge has remained an open research challenge. Existing frameworks do not cope with problems such as multiple user viewpoints, the plurality of epistemologies and representational forms, the mutability of knowledge, and the ...
Pigott, Diarmuid, Diarmuid J Pigott
core  

Conceptual modeling for simulation [PDF]

2013 Winter Simulations Conference (WSC), 2013
openaire   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Healthcare Professionals' Subjective Well-Being: A Systematic Review and Methodological Appraisal of Conceptual Models, Measurement Instruments, and Associated Factors. [PDF]

Int J Environ Res Public Health
Skrūzkalne I, Nagle E, Andersen O, Perevozčikova J, Sakkeus L, Kairys A, Griškēviča I, Seņkāne S, Ivanovs A, Reine I.   +9 more
europepmc   +1 more source

Uncertainty in Decision Making in Medicine: A Scoping Review and Thematic Analysis of Conceptual Models. [PDF]

Acad Med, 2020
Helou MA, DiazGranados D, Ryan MS, Cyrus JW.   +3 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source