Results 171 to 180 of about 8,079,181 (257)

An exploratory analysis on the comprehension of 3D and 4D ontology-driven conceptual models

, 2016
In this paper, we perform an exploratory analysis to investigate the impact of adopting a 3D and a 4D foundational ontology on the quality of a conceptual model.
Verdonck, MichaëlEB240000705909408020017536150000-0002-1927-315107F014EA-F0EE-11E1-A9DE-61C894A0A6B4, Link, Sebastianeditor, Gailly, FrederikEB24EB580019973048698010016586560000-0003-0481-9745F683AB4A-F0ED-11E1-A9DE-61C894A0A6B4, Trujillo, Juan Ceditor   +3 more
core  

The Theory of Relationship Sabotage: A Preliminary Evaluation of Conceptual Models Expanding on Attachment and Goal-Orientation Frameworks. [PDF]

Behav Sci (Basel)
Peel R.
europepmc   +1 more source

Remission in adolescents with bulimia nervosa: Empirical evaluation of current conceptual models. [PDF]

Eur Eat Disord Rev, 2020
Gorrell S, Matheson BE, Lock J, Le Grange D.   +3 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Pedagogical Strategies for Teaching Conceptual Models and Nursing Theories in Undergraduate Students: A Scoping Review. [PDF]

J Adv Nurs
Demagny-Warmoes A, Duchadeau M, Quindroit P, Colson S.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Conceptual Models for Understanding an

, 2000
Conceptual models are one of many resources available to pilots for making sense of the flight environment. In this paper we describe the conceptual models a pilot uses, in interviews, to explicate his encounter with a mountain wave while flying an ...
Encounter With Mountain, Edwin Hutchins, Barbara Holder   +2 more
core  

Evaluation of LSTM vs. conceptual models for hourly rainfall runoff simulations with varied training period lengths. [PDF]

Sci Rep
Fathi MM, Al Mehedi MA, Smith V, Fernandes AM, Hren MT, Terry DO.   +5 more
europepmc   +1 more source

Development of Conceptual Models to Guide Public Health Research, Practice, and Policy: Synthesizing Traditional and Contemporary Paradigms. [PDF]

Health Promot Pract, 2020
Brady SS, Brubaker L, Fok CS, Gahagan S, Lewis CE, Lewis J, Lowder JL, Nodora J, Stapleton A, Palmer MH, Prevention of Lower Urinary Tract Symptoms (PLUS) Research Consortium.   +10 more
europepmc   +1 more source