Results 41 to 50 of about 36,417 (176)

Understanding Predication in Conceptual Spaces

open access: yes, 2016
We argue that a cognitive semantics has to take into account the possibly partial information that a cognitive agent has of the world. After discussing Gärdenfors's view of objects in conceptual spaces, we offer a number of viable treatments of partiality of information and we formalize them by means of alternative predicative logics.
Masolo Claudio, Porello Daniele
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Emotions in conceptual spaces

open access: yesPhilosophical Psychology
The overreliance on verbal models and theories in psychology has been criticized for hindering the development of reliable research programs (Harris, 1976; Yarkoni, 2020). We demonstrate how the conceptual space framework can be used to formalize verbal theories and improve their precision and testability.
Michał Sikorski, Ohan Hominis
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Organizational Food Environments: Advancing Their Conceptual Model

open access: yesFoods, 2022
Understanding the complexity of the elements that constitute organizational food environments and their operating dynamics is essential to improving their healthiness. This study developed a conceptual model of organizational food environments.
Inês Rugani Ribeiro de Castro   +1 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Zur temporalen Entfaltung und multimodalen Orchestrierung von konzeptuellen Räumen am Beispiel einer Erzählung

open access: yesLinguistik Online, 2020
The study presented in this article investigates the temporal unfolding and multimodal orchestration of meaning in a narration. Two aspects are focused on.
Silva Ladewig, Lena Hotze
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Images of Ukraine-EU relations in conceptual metaphors of Ukrainian mass media

open access: yesКогниция, коммуникация, дискурс, 2018
This paper discusses the system of conceptual metaphors reconstructed via analysis of metaphorical expressions (ME) employed by eight popular Ukrainian newspapers (Holos Ukrainy, Uriadovyi Kurier, Den', Dzerkalo Tyzhnya, Gazeta Po-Ukrains'ky, Segodnya ...
Svitlana Zhabotynska
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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