Results 71 to 80 of about 36,417 (176)

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

An ancient olive tree in the garden. Mapping the deep history of land use from a single image

open access: yesGeocarto International
Landscapes with a deep history of land use are the legacy of millennial interactions between ecological, social and cultural elements, which can be investigated to obtain new knowledge about our present-day ecosystems. This paper presents the application
Vincenza Ferrara, Anders Wästfelt
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Conceptualizing space environmental sustainability

open access: yesnpj Advanced Manufacturing
AbstractRecent advancements have significantly enhanced the capabilities for in-space servicing, assembly, and manufacturing (ISAM), to develop infrastructure in orbit and on the surface of celestial bodies. This progress is a departure from the traditional sustainability paradigm focused solely on Earth, highlighting the urgent need to define and ...
Weiwei Mo   +6 more
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Exploring Successful Small Urban Spaces’ Criteria with Emphasis on Cultural Context

open access: yesTehnički Glasnik, 2021
In the crowded cities of the present age, public spaces can provide a quiet area away from the hustle and bustle of the city that citizens can interact with by incorporating utility features and meeting human needs and Relax there. Small urban spaces are
Parvin Partovi   +2 more
doaj  

Blending versus conceptual interaction in the construction of illocutionary meaning: counterfactual pieces of advice

open access: yesRevista Alicantina de Estudios Ingleses, 2002
The cognitive operation of conceptual integration or blending as described by Fauconnier and Turner (1994,1996) includes the notion of emergent structure, that is to say, conceptual structure, which is part of the blend and which is independent and/or ...
Pérez Hernández, Lorena
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

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