Results 121 to 130 of about 7,797,471 (373)

Impact of Learning Model Based on Cognitive Conflict toward Student’s Conceptual Understanding

, 2018
The problems that often occur in the learning of physics is a matter of misconception and low understanding of the concept. Misconceptions do not only happen to students, but also happen to college students and teachers.
F. Mufit, F. Festiyed, Ahmad Fauzan, L. Lufri   +3 more
semanticscholar   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Gender differences in conceptual understanding of Newtonian mechanics: a UK cross-institution comparison

, 2012
We present results of a combined study from three UK universities where we investigate the existence and persistence of a performance gender gap in conceptual understanding of Newtonian mechanics.
Bates, Simon, Birch, Marion, Donnelly, Robyn, MacPhee, Cait, Sands, David, Walet, Niels R.   +5 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

A second order cybernetic model of scientific conceptual understanding with pedagogical applications to kinematics [PDF]

Journal of Systemics, Cybernetics and Informatics, 2012
Even if difficulties of the students in sciences are diversified, most seem linked to deficiencies in their understanding of basic concepts. Since about twenty years, different researches tried to bring solutions in this problem, favouring the ...
Louis Trudel, Abdeljalil Métioui
doaj  

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Pemahaman Konsep Matematika Siswa pada Materi Besar Sudut Melalui Pendekatan PMRI

Jurnal Gantang, 2017
Penulisan artikel ini bertujuan untuk memaparkan hasil pemahaman konsep matematika siswa pada materi besar sudut di kelas VI Sekolah Dasar (SD) melalui pendekatan PMRI.
Pramitha Sari
doaj  

How do enhanced videos support generative learning and conceptual understanding in individuals and groups? [PDF]

Educ Technol Res Dev, 2023
Ruf A, Zahn C, Roos AL, Opwis K.
europepmc   +1 more source

Goal → New Heuristic Model of Ideality: Logos → Coincidentia Oppositorum → Primordial Generating Structure [PDF]

, 2017
Fundamental knowledge endures deep conceptual crisis manifested in total crisis of understanding, crisis of interpretation and representation, loss of certainty, troubles with physics, crisis of methodology. Crisis of understanding in fundamental science
Rogozhin, Vladimir
core