Results 121 to 130 of about 2,257,218 (320)

Pre-service Teachers' Use of Technology as Reorganizer to Promote Differing Levels of Conceptual Understanding. [PDF]

Digit Exp Math Educ, 2022
Davis JD, Witt NE.
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Co-constructing a Conceptual Understanding of System Enactment. [PDF]

Clin Soc Work J, 2022
Morey CM.
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Algebraic symbolism as a conceptual barrier in learning mathematics [PDF]

, 2013
The use of symbolism in mathematics is probably the mostly quoted reason people use for explaining their lack of understanding and difficulties in learning mathematics. We will consider symbolism as a conceptual barrier drawing on some recent findings in
Heeffer, Albrecht
core  

Seeing Yourself in the Past: The Role of Situational (Dis)continuity and Conceptual Metaphor in the Understanding of Complex Cases of Character Perception [PDF]

, 2016
Maarten Coëgnarts, Miklós Kiss, Peter Kravanja, Steven Willemsen   +3 more
openalex   +1 more source

Development and Validation of a Four-Tier Test for the Assessment of Secondary School Students' Conceptual Understanding of Amino Acids, Proteins, and Enzymes. [PDF]

Res Sci Educ, 2023
Putica KB.
europepmc   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

An Exploration of Students’ Misconceptions about the Concept ‘Classification of Animals’ at Secondary Level and Effectiveness of Inquiry Method for Conceptual Change

Ankara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2013
Research has provided overwhelming evidence that children enter in science classroom with ideas they have formed in making sense of the world around them.
Anjum NAZ, Abida NASREEN
doaj  

Investigating the Impact of Visuohaptic Simulations for Conceptual Understanding in Electricity and Magnetism [PDF]

, 2020
Karla Sanchez, Alejandra J. Magana, David Sederberg, Grant Richards, M. Gail Jones, Hong Z. Tan   +5 more
openalex   +1 more source