Results 71 to 80 of about 306,552 (260)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Scholaria: Jurnal Pendidikan dan Kebudayaan, 2018 In learning Mathematics, conceptual understanding is a primary competency that the students must acquire, because through understanding the concept the students would understand what is being learned and are able to apply them thus they can pursue ...
Jhon Tetiwar, Oce Datu Appulembang
doaj
A second order cybernetic model of scientific conceptual understanding with pedagogical applications to kinematics [PDF]
Journal of Systemics, Cybernetics and Informatics, 2012 Even if difficulties of the students in sciences are diversified, most seem linked to deficiencies in their understanding of basic concepts. Since about twenty years, different researches tried to bring solutions in this problem, favouring the ...
Louis Trudel, Abdeljalil Métioui
doaj
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Kinematics Conceptual Understanding: Interpretation of Position Equations as a Function of Time
Jurnal Pendidikan Sains, 2019 : This article aims at describing the ability of 48 students of physics education in determining distance traveled, average speed, and acceleration of position functions.
Muhammad Reyza Arief Taqwa, Lugy Rivaldo
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Berkala Ilmiah Pendidikan Fisika, 2019 In learning physics, the problem that arises is a lack of physics conceptual understanding in contextual learning. These problems are due to the absence of innovative and creative learning resources that can be used to learn by the students.
Betti Ses Eka Polonia, Lia Yuliati
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source