Results 101 to 110 of about 255,089 (293)
Legal Regulation Of Commercial Concessions (Franchising) In Accordance With Russian And Foreign Law
Astra Salvensis, 2019 The purpose of this work is to define the legal systems on commercial concession (franchising) regulation in the world practice, and also identification of the specifics of commercial concession contractual regulation in Russia, and analysis of all ...
Elmira Failovna GUMEROVA +2 more
doaj
An enunciative approach to discourse markers: yet and still [PDF]
Studii de Lingvistica, 2015 The present study aims to provide a general model for the analysis of discourse markers, formulated within the Theory of Enunciative and Predicative Operations (TEPO) (cf. Culioli 1990, 1999a, 1999b). Discourse marking is seen as a
Graham Ranger
doaj
Why It Is So Hard? A History of Highway Concession Contracts in Poland [PDF]
In this paper we analyze the early stages of the highway construction program in Poland. We argue that the whole investment process could be accelerated if much attention was paid to establishing a better legal framework.
Barbara Despiney, Waldemar Karpa
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The story of the UK oil and gas taxation policy: history and trends [PDF]
, 2010 Different oil producing countries adopt different types of oil and gas agreements to regulate their relationships with international oil and gas companies. These countries tailor petroleum fiscal regimes to fit their own desires. However, in some cases a
Abdo, H
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Privatization of infrastructure ventures in sectors such as energy, telecommunication, transport, and water has become popular over the last decade. Often- for good or bad reasons - private firms are given monopoly franchises under some type of long-term
Klein, Michael
core
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Prolegomena : Časopis za filozofiju, 2013 In the first, shorter part of the paper I point out some problems and potential misunderstandings connected with B. Berčić's treatment of Nozick's sensitivity condition for knowledge. In the second part of the paper I offer the condition of modal stability or limited sensitivity as a revision of Nozickian conditions for non-accidental connection ...
openaire +2 more sources