Results 121 to 130 of about 71,233 (350)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Legal Regulation Of Commercial Concessions (Franchising) In Accordance With Russian And Foreign Law
Astra Salvensis, 2019 The purpose of this work is to define the legal systems on commercial concession (franchising) regulation in the world practice, and also identification of the specifics of commercial concession contractual regulation in Russia, and analysis of all ...
Elmira Failovna GUMEROVA +2 more
doaj
An enunciative approach to discourse markers: yet and still [PDF]
Studii de Lingvistica, 2015 The present study aims to provide a general model for the analysis of discourse markers, formulated within the Theory of Enunciative and Predicative Operations (TEPO) (cf. Culioli 1990, 1999a, 1999b). Discourse marking is seen as a
Graham Ranger
doaj
, 2016 U pravnom smislu, koncesija predstavlja dozvolu za obavljanje neke djelatnosti uvjetovana posebnim odobrenjem, te su koncesije dvostrani pravni odnosi, što znači da se uvijek razvijaju između dviju strana, odnosno između davatelja koncesije i ...
Barišić, Suzana
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
McCain's 2008 presidential concession
, 2010 This thesis examines Senator John McCain’s concession address from the 2008 United States Presidential election campaign. McCain’s concession speech was significant because of his come-from-behind victory in the Republican primary, the favorable critical
Mills, Elizabeth A.
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Evaluation of Nigerian ports post-concession performance
Concession has been acknowledged as a valuable tool for port authorities to retain control of ports and shape the supply side of the terminal market, in the absence of full privatisation.
Nwanosike, F.
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source