Results 121 to 130 of about 255,089 (293)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The impact of private provision of public education: Empirical evidence from Bogota's concession schools [PDF]

open access: yes, 2012
In 1999, the city of Bogotá, Colombia launched the Concession School program designed to broaden the coverage and quality of basic education. It consists of a contract between a group of private schools and the public educational system such that private
Barrera-Osorio, Felipe
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Statute şi decizii privind concesiunea de omnibusuri şi fiachere în Comitatul Braşov / Statutes and decisions on the concession on omnibuses and fiacres in the Braşov County

open access: yesTyragetia, 2016
Based on the study of documents from the collections of the Braşov County Museum of History, the author provides information on the concession on public transport in the municipalities of the Braşov County at the end of the 19th century.
Cristina Tănase
doaj  

History of concession agreements development in Russia

open access: yesВестник университета
The history of concession agreements in Russia spans more than a century, from the late 19th century to the present day. Initially, concessions played a key role in attracting foreign investment and developing infrastructure in the Russian Empire. During
V. Ya. Afanasyev, N. A. Kalyuzhnaya
doaj   +1 more source

Concession contract renegotiations : some efficiency versus equity dilemmas [PDF]

open access: yes
The authors analyze the possibility of tradeoffs between efficiency and equity as well as the possibility of distributional conflicts in the context of renegotiation of infrastructure contracts in developing countries.
Estache, Antonio, Quesada, Lucia
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

U.A.W. 50th Anniversary Anti-Concession Rally 1987- Victor Reuther Part B [PDF]

open access: yes, 2005
This article is part of the collection of writings of Marshall (Mike) Westfall, retired autoworker from General Motors in Flint, Michigan (1964-1994) and activist critic of the auto industry restructuring that led to devastating job losses. It originally
Westfall, Marshall (Mike)
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Uvođenje općeg stvarnopravnog režima na objektima lučke suprastrukture izgrađenim na temelju ugovora o koncesiji

open access: yesPoredbeno Pomorsko Pravo, 2015
U tijeku rasprave o radnom materijalu nacrta prijedloga Zakona o pomorskom dobru i morskim lukama ponovo se aktualiziralo pitanje uspostave općeg stvarnopravnog režima na zgradama i drugim građevinama koje su izgrađene na pomorskom dobru na temelju ...
Loris Rak   +2 more
doaj  

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