Results 61 to 70 of about 281,352 (293)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Incorporation of foreign timber concessions in Soviet Russia in the 1920s

open access: yesRUDN Journal of Law
The article based on legislative acts of Soviet Russia and unpublished sources of the State Archive of the Arkhangelsk Oblast, describes the features of incorporation of Russangloles, Russhollandoles and Russnorvegoles joint-stock companies, operating in
Oleg. V. Minchuk   +2 more
doaj   +1 more source

Industrial concessions, fires and air pollution in Equatorial Asia

open access: yesEnvironmental Research Letters, 2015
Forest and peatland fires in Indonesia emit large quantities of smoke leading to poor air quality across Equatorial Asia. Marlier et al (2015 Environ. Res. Lett.
D V Spracklen   +2 more
doaj   +1 more source

Algunas reflexiones sobre las distintas alternativas existentes para financiar el mantenimiento y conservación de las carreteras españolas

open access: yesRevista Vasca de Administración Pública, 2021
There are different financing models for the maintenance of Spanish roads, which are based either on gratuity for road users or on payment for the use of such infrastructures.
Javier Esteban Ríos
doaj   +1 more source

Recent Union Contract Concessions [PDF]

open access: yes
macroeconomics, union ...
Daniel J. B. Mitchell
core  

Multiple-use forest management in Central Africa: Perceptions, implementation and evolution [PDF]

open access: yes, 2011
Although multiple-use forest management (MUFM) is supported by forestry laws in the Congo Basin countries, this approach remains confused, misunderstood and little implemented.
Essoungou, Julienne Nadège   +1 more
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Current legislative framework for public-private partnership and concessions in Serbia [PDF]

open access: yesEkonomija: teorija i praksa, 2018
When it comes to public-private partnerships in the Republic of Serbia, there has been an evident lack of adequate and supportive legal framework for many years. The first law in this area was adopted in 2011.
Matijašević-Obradović Jelena   +1 more
doaj  

Road Infrastructure Financing Models

open access: yesPromet (Zagreb), 2007
Already in its early phase, starting with initial general needsof people to survive and find food, traffic and traffic se1viceturned into a modern system which increased the complexityand interdependence within the traffic system, and then withthe ...
Rajko Horvat   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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