Results 61 to 70 of about 8,293 (246)

The Social Structure and Ideology of the Rebel Movement in Yakutia during 1921–1922

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
As part of the complex research on the Yakut anti-Soviet rebel movement in 1921–1922, which rose to the national level, the social structure and ideology of the rebels have been considered.
E.P. Antonov, V.N. Antonova
doaj  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

CONCESSIONS ON THE MARITIME DOMAIN – THE RELATION OF THE CONCESSIONS ACT AND THE MARITIME DOMAIN AND SEAPORTS ACT

open access: yesPravni Vjesnik, 2017
In this paper, the authors analyse the legislative framework of concessions on maritime domain. The Maritime Domain and Seaports Act passed in 2003 prescribes concessions on maritime domain.
Frane Staničić, Maja Bogović
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Gestión del agua subterránea en los acuíferos de la cuenca del río Ayuquila-Armería en Jalisco y Colima, México

open access: yesRegión y Sociedad, 2019
El objetivo de este artículo es analizar el papel de las concesiones de agua subterránea inscritas en el Registro Público de Derechos de Agua, como instrumento de planeación para el agua subterránea en la cuenca del río Ayuquila-Armería.
Rodrigo Alejandro Hernández Juárez   +3 more
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

New legal framework of concessions in Croatia

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2014
At the end of 2012, Republic of Croatia put into force new Concessions Act, adjusted to the Proposal for a Directive of the European Parliament and of the Council on the award of concession contract from 2011. New Act is an important change on concession
Goran Vojković
doaj  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

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