Results 71 to 80 of about 37,492 (304)
Political Risk and Regulatory Risk: Issues in Emerging Markets Infrastructure Concessions [PDF]
Political and regulatory risks, cause damage to countries and investors because of investment diminishing. When investments take place, those could increase services prices. Present work has as its objectives to characterize theoretically the problem, to
Ferro, Gustavo
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Current legislative framework for public-private partnership and concessions in Serbia [PDF]
When it comes to public-private partnerships in the Republic of Serbia, there has been an evident lack of adequate and supportive legal framework for many years. The first law in this area was adopted in 2011.
Matijašević-Obradović Jelena +1 more
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Auctions for Infrastructure Concessions with Demand Uncertainty and Unknown Costs [PDF]
Auction mechanisms commonly used in practice for awarding infrastructure concession contracts induce a bias towards the selection of concessionaires who are optimistic about demand, but are not necessarily cost-efficient.
de Rus, Gines, Nombela, Gustavo
core
Tax concessions in support of charitable giving: an international comparison [PDF]
The Australian taxation system encourages charitable giving through tax deductibility for donations made by individuals and companies, and via tax exemption for income distributed to charities through charitable trusts.
Smith, Greg
core
Public-private partnership acts as a form of effective interaction between the public partner and private investors in order to solve various social problems.
Fail Ibyatov
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
PUBLIC-PRIVATE PARTNERSHIPS (PPPs) AND CONCESSIONS OF PUBLIC SERVICES IN BRAZIL
This paper examines the current regulation of public-private partnerships (PPPs) and concessions of public services inBrazil. Under the Brazilian Constitution, certain public utility services and infrastructure works must be provided or built either ...
C. A. G. Pereira
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

