Results 191 to 200 of about 834,266 (237)

[Initial clinical experience with ribociclib in advanced HR+/HER2- breast cancer in Uruguay]. [PDF]

Rev Med Inst Mex Seguro Soc
Camejo-Martínez N, Strazzarino-Peluffo N, Amarillo-Hernández C D, Castillo-Leska C, Krygier-Waltier G.   +4 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

[Early virological failure with long-acting cabotegravir/rilpivirine: description of two cases]. [PDF]

Rev Esp Quimioter
Pena-López MJ, Torres-Martel EG, Santana-Baez S, Bosch-Guerra X.   +3 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

[Comprehensive approach to comorbidities in COPD: expert recommendations]. [PDF]

Open Respir Arch
de Miguel-Díez J, Figueira Gonçalves JM, Ji Z, Pascual Guardia S, Represas C.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

[Indications for lumbar spine radiography in Primary Care: interpretation beyond the image]. [PDF]

Aten Primaria
Toranzo-Benítez J, Aispuru-Lanche R.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Resúmenes presentados al 36 Congreso de la Asociación de Cardiología Intervencionista de la Sociedad Española de Cardiología. Santiago de Compostela, 4-6 de junio de 2025. [PDF]

REC Interv Cardiol
europepmc   +1 more source

[Progress and controversies in prediabetes. Is a more holistic approach needed?] [PDF]

Aten Primaria
Apiñaniz Fernández de Larrinoa A, Cobos Campos R.   +1 more
europepmc   +1 more source