Results 181 to 190 of about 834,266 (237)

Comunicaciones LX Reunión Anual SENFC Barcelona, 2 a 4 de octubre de 2024. [PDF]

Rev Neurol
europepmc   +1 more source

Limitaciones metodológicas del artículo “Factores de riesgo para colecistitis aguda gangrenosa”. [PDF]

Acta Gastroenterol Latinoam
Palomares Rutte JF, Chambi Mejía YC.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

[Characterization of immune reconstitution inflammatory syndrome in a Mexican cohort]. [PDF]

Rev Med Inst Mex Seguro Soc
Palma-Díaz EJ, Albarrán-Sánchez A, Noyola-García ME, Pérez-Pedraza EE.   +3 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

[An overview of home care for patients with chronic diseases in Latin America: A scoping reviewPanorama da atenção domiciliar para pacientes com doenças crônicas na América Latina: revisão de escopo]. [PDF]

Rev Panam Salud Publica
Fonseca Valencia C, Botero Toro A, Forero AP, González-Rodríguez J, Pinzón Espitia OL, Murcia-Soriano LF.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Conclusiones finales

Antigüedad y Cristianismo, 2000
José Antonio Molina Gómez
doaj  

[Efficiency after integrating a hospital with a 'new management model']. [PDF]

An Sist Sanit Navar
Cacho Uzal M, Cueva Ares J, Lopez-Juiz F, Reyes Santías F.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source