Results 201 to 210 of about 2,395,880 (254)

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

The synthesis of evidence and its pedagogical application: the dualism present in the Revista Colombiana de Obstetricia y Ginecología [PDF]

Rev Colomb Obstet Ginecol
Grillo-Ardila CF.
europepmc   +1 more source

Conclusiones políticas y líneas de trabajo a futuro [PDF]

, 2010
AFUTU, Asociacion de Funcionarios de la Universidad de Trabajo del Uruguay - Autor/a, CNTE, Coordinadora Nacional de Trabajadores de la Educación - Autor/a, Colegio de Profesores - Autor/a, CTERA, Confederación Trabajadores de la Educación de la República Argentina - Autor/a, FENAPES, Federación Nacional de Profesores de Educación Secundaria - Autor/a, LPP, Laboratorio de Políticas Públicas - Autor/a   +5 more
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

[Transition in mental health from childhood to adulthood: A scoping review]. [PDF]

An Sist Sanit Navar
Guerra-Ortega ADC, Rodríguez-Suárez CA, González-de la Torre H.   +2 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Capítulo 8: Conclusiones

Antigüedad y Cristianismo, 2001
María Gloria Guillén Pérez de Ploch
doaj  

[Experience with medical treatment using sirolimus for cardiac rhabdomyomas in children. A case series]. [PDF]

Arch Cardiol Mex
Stelmaszewski EV, Olivetti ME, Diez-Mori F, Salgado G.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Letter to the Editor about “Preoperative neutrophil/ lymphocyte ratio as prognostic factor in epitelial ovarian cancer” [PDF]

Rev Colomb Obstet Ginecol
Cesar Huamanciza LÁ.
europepmc   +1 more source