Results 51 to 60 of about 613,046 (357)

P‐glycoprotein modulates the fluidity gradient of the plasma membrane of multidrug resistant CHO cells

FEBS Letters, EarlyView.
To explore the impact of the overexpression of the multidrug‐transporter P‐glycoprotein (ABCB1) on membrane fluidity, we compared the transversal gradient of mobility and microviscosity in plasma membranes of drug‐sensitive Chinese hamster ovary cells (AuxB1) and their multidrug‐resistant derivatives (B30) using the fluorescent n‐(9‐anthroyloxy) fatty ...
Roger Busche, John R. Riordan, Burkhard Tümmler   +2 more
wiley   +1 more source

Inteligencia artificial y problemas de decisión: la necesidad de un contexto ético

Suma de Negocios, 2021
Los computadores procesan información y toman decisiones. Hasta hace poco, las decisiones que tomaban no eran complejas, pero debido a los incesantes avances tecnológicos que se producen, los sistemas basados en inteligencia artificial están logrando ...
José Luis Verdegay, M.ª Teresa Lamata , David Pelta , Carlos Cruz   +3 more
doaj   +1 more source

Rethinking serializable multiversion concurrency control [PDF]

Proceedings of the VLDB Endowment, 2014
Multi-versioned database systems have the potential to significantly increase the amount of concurrency in transaction processing because they can avoid read-write conflicts.
Jose M. Faleiro, D. Abadi
semanticscholar   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Could differences in implicit attitudes to sexual concurrency play a role in generalized HIV epidemics? [version 2; referees: 2 approved]

F1000Research, 2018
Background: Sexual partner concurrency has been implicated in the genesis of generalized HIV epidemic in South Africa. Most South Africans, however, disapprove of concurrency in surveys.
Chris R. Kenyon, Kenny Wolfs, Kara Osbak, Maleeto Malataliana, Guido Van Hal, Sizwe Zondo, Jacques van Lankveld   +6 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Concurrent sexual partnerships and associated factors: a cross-sectional population-based survey in a rural community in Africa with a generalised HIV epidemic

BMC Public Health, 2011
Background Although concurrent sexual partnerships may play an important role in HIV transmission in Africa, the lack of an agreed definition of concurrency and of standard methodological approaches has hindered studies.
Karabarinde Alex, Waswa Laban, Maher Dermot, Baisley Kathy   +3 more
doaj   +1 more source

Specifying Internet of Things Behaviors in Behavior-Driven Development: Concurrency Enhancement and Tool Support

Applied Sciences, 2023
The Internet of Things (IoT) systems are inherently distributed with many concurrent behaviors. In order to apply behavior-driven development (BDD), a proven agile practice of software development that brings many benefits, we must ensure that the ...
Bing-Yun Wang, Yi-Chun Yen, Yu Chin Cheng   +2 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Concurrence geometries

Advances in Mathematics, 1983
The paper deals with the problem ''to describe combinatorially the variety of configurations c of hyperplanes which can be constructed, given that the section of the configuration c on a fixed hyperplane H be a given geometric figure''. This is related to a correspondence between plane projections of polyhedra in 3-space and static stresses in the ...
openaire   +2 more sources