Results 81 to 90 of about 613,046 (357)
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Measuring Overhead of Concurrency and Virtual Memory
Моделирование и анализ информационных систем, 2018 We present the methodology, as well as results of measurements and evaluation of overhead created by concurrency and virtual memory. A special measurement technique and testbed were used to obtain the most accurate data from the experiments.
Yauhen Klimiankou
doaj +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
Architecting software concurrency [PDF]
Computer Science Journal of Moldova, 2011 Nowadays, the majority of software systems are inherently concurrent. Anyway, internal and external concurrent activities increase the complexity of systems' behavior. Adequate architecting can significantly decrease implementation errors.
Dumitru Ciorba, Victor Besliu
doaj
Managing GPU Concurrency in Heterogeneous Architectures
Micro, 2014 Heterogeneous architectures consisting of general-purpose CPUs and throughput-optimized GPUs are projected to be the dominant computing platforms for many classes of applications.
Onur Kayiran +7 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti +5 more
wiley +1 more source
Improving GPGPU concurrency with elastic kernels
International Conference on Architectural Support for Programming Languages and Operating Systems, 2013 Each new generation of GPUs vastly increases the resources available to GPGPU programs. GPU programming models (like CUDA) were designed to scale to use these resources.
Sreepathi Pai +2 more
semanticscholar +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
FEBS Open Bio, EarlyView.The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source