Results 81 to 90 of about 190,212 (326)
Applied SciencesMobile users can access vital real-time services through wireless paradigms like software-defined network (SDN) topologies and the Internet of Things. Point-of-contact-based infrastructures and dynamic user densities increase resource access and service ...
Mohd Anjum, Hong Min, Zubair Ahmed
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
BMC Public Health, 2011 Background Although concurrent sexual partnerships may play an important role in HIV transmission in Africa, the lack of an agreed definition of concurrency and of standard methodological approaches has hindered studies.
Karabarinde Alex +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Debugging real-time software in a host-target environment [PDF]
, 1984 A common paradigm for the development of process-control or embedded computer software is to do most of the implementation and testing on a large host computer, then retarget the code for final checkout and production execution on the target machine. The
Taylor, Richard N.
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Architecting software concurrency [PDF]
Computer Science Journal of Moldova, 2011 Nowadays, the majority of software systems are inherently concurrent. Anyway, internal and external concurrent activities increase the complexity of systems' behavior. Adequate architecting can significantly decrease implementation errors.
Dumitru Ciorba, Victor Besliu
doaj
Partner concurrency and HIV infection risk in South Africa
International Journal of Infectious Diseases, 2016 Background: The relationship between concurrent sexual partnerships and HIV risk is not fully understood. Evidence on the relationship between partner concurrency (one's sexual partner has another partner) and individual HIV risk is limited.
Chris R. Kenyon +3 more
doaj +1 more source
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
On CSP and the Algebraic Theory of Effects
, 2010 We consider CSP from the point of view of the algebraic theory of effects, which classifies operations as effect constructors or effect deconstructors; it also provides a link with functional programming, being a refinement of Moggi's seminal monadic ...
B Scattergood +12 more
core +2 more sources