Results 61 to 70 of about 139,918 (259)

Effects of Concurrent Training (Resistance-Endurance) on Interferon-γ, Interloukin-18 and Transforming Growth Factor-β Gene Expression in Women with Type 2 Diabetes

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2020
Introduction: High-intensity training increases the expression of anti-inflammatory cytokines and decreases the expression of pre-inflammatory cytokines in healthy individuals.
, Amirabbas monazzami, ,
doaj  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Latest advances and controversies of exercise therapy in the management of type 2 diabetes

Frontiers in Endocrinology
Exercise therapy is a recognized cornerstone in the management of type 2 diabetes, offering broad benefits that extend beyond simple glycemic control to include cardiovascular and quality-of-life improvements. This mini-review synthesizes recent evidence
Jiaman Hao, Huiyan Zhang, Huiyan Zhang
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Comparison of Different Time Course of Concurrent Training on Lipid Profile and Total Antioxidant in Cardiac Patients

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2022
Introduction: Oxidative stress is involved in the pathogenesis of many diseases, including atherosclerosis. Lipid profile conditions, oxidative stress and antioxidant imbalances play a major role in the development of the disease.
Najmeh Ranjbar, Seyed Mohammad Marandi, Seyedeh Mahdieh Namayandeh, Jalil Mirhosseini, Mahdieh Ghanbery   +4 more
doaj  

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The concurrent training effect

, 2021
Η συνδυαστική προπόνηση (concurrent training) ορίζεται ως ταυτόχρονη προπόνηση δύναμης και αντοχής σε ένα περιοδισμένο προπονητικό πρόγραμμα. Παρά τα πιθανά προσθετικά οφέλη που προκύπτουν από τον συνδυασμό αυτών των διαφορετικών μεθόδων, όπως η πρόληψη τραυματισμών αλλά και η απόδοση στον αθλητισμό, υπάρχουν στοιχεία που αποδεικνύουν ότι η προσέγγιση ...
openaire   +1 more source