Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Reply to: Neutron diffraction evidence of the 3-dimensional structure of Ba<sub>2</sub>MnTeO<sub>6</sub> and misidentification of the triangular layers within the face-centred cubic lattice. [PDF]
Khatua J +8 more
europepmc +1 more source
Short overview of the 4th international conference on materials science and condensed matter physics
openaire +1 more source
Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun +27 more
wiley +1 more source
Isostructural electronic transition in MoS<sub>2</sub> probed by solid-state high-harmonic generation spectroscopy. [PDF]
Nebgen BR +7 more
europepmc +1 more source
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
Symmetry-locked six-state control of altermagnetism via sliding ferroelectricity. [PDF]
Sun W, Wang W, Yang C, Huang S, Cheng Z.
europepmc +1 more source
Comparative genomics of Gondwana‐diverged Pila and Pomacea reveals parallel evolution of aerial oviposition. Convergent chromosomal rearrangements reshape regulatory landscapes within topologically associating domains. Lineage‐specific gene family expansions and viral‐derived perivitelline proteins (PV1) underpin desiccation resistance.
Yufei Zhou +10 more
wiley +1 more source
Bio-derived tannic acid-Eu(iii) coordination synergizes with aluminum diethylphosphinate for low-loading and high-efficiency flame retardancy in PA66. [PDF]
Liu Z +6 more
europepmc +1 more source
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu +11 more
wiley +1 more source

